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The Journey of APIs through COVID-19

The active pharmaceutical ingredients (API) market was worth approximately USD 177.05 billion in 2021 and is expected to reach USD 258.60 billion by 2027, growing at a CAGR of nearly 7.50 percent between 2022 and 2027.

The COVID-19 outbreak had a positive impact on the market in 2020, as countries and major players manufactured large amounts of ingredients to meet the demand for COVID-19 treatment. The COVID-19 pandemic has prompted drug companies to refocus their models on a larger patient population. For example, the United States requested that coronavirus treatment hydroxychloroquine (HCQ) be imported from India. The virus has also disrupted the Canadian drug supply chain, potentially causing problems for Canadian patients.

The rising prevalence of chronic diseases is expected to increase drug demand, fuelling the growth of the active pharmaceutical ingredients market shortly. The World Health Organization (WHO) reports that cardiovascular diseases are the leading cause of death worldwide, claiming an estimated 17.9 million lives each year.

According to the Alzheimer’s Association, approximately 5.8 million people in the United States will have Alzheimer’s disease by 2020. This disease is the sixth leading cause of death in the United States, and it is more common in people over the age of 65. (And approximately 5.6 million patients fall in this age bracket).

Furthermore, the companies’ strategic initiatives to maintain market stability include the launch of new drugs and biological products, acquisitions, collaborations, and regional expansions. This will almost certainly fuel market growth shortly. For example, Quartic.ai and Bright Path Labs collaborated in 2020 to develop AI-based technology for the continuous manufacturing of critical APIs required for the production of critical small-molecule drugs.

Drugs such as anti-infectives, diabetes, cardiovascular, analgesics, and pain management drugs have traditionally dominated the active pharmaceutical ingredients (API) market. However, according to R&D trends, the demand for complex APIs used in novel formulations targeting niche therapeutic areas is increasing.

Drug price control policies in various countries, fierce competition among existing players, and stringent regulatory policies are the major factors limiting the market growth. ​

The APIs, however, saw a spike in the growth rate of their market globally during the period as shown here.

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